Breakthrough: Scientists May Have Found A Cure For Baldness Caused By Alopecia Areata

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Breakthrough: Scientists May Have Found A Cure For Baldness Caused By Alopecia Areata

August 2014

 

A drug approved to treat a rare form of leukemia reversed hair loss caused by alopecia, a small study found.

The drug, ruxolitinib, helps reduce inflammation caused by disease. But it also helped three alopecia sufferers regrow full heads of hair within five months, according to the study published Sunday in the journal Nature Medicine.

“We still need to do more testing to establish that ruxolitinib should be used in alopecia,” said study author Dr. Raphael Clynes, director of the Columbia Center for Translational Immunology at Columbia University in New York City. “But this is exciting news for patients and their physicians.”

Alopecia is an autoimmune disease that leads to patchy hair loss. It is not the same as male pattern baldness, which has its roots in genetic and hormonal causes.

It’s not yet known if ruxolitinib can restore other types of hair loss.

The drug is just one of a few hair restoration treatments currently being tested. Here’s a rundown of four more follicular helpers that have shown some promise.


For millions of individuals worldwide who have receding hairlines, an experimental pill may just be the ultimate solution for their hair loss and baldness problems.

After identifying the immune cells responsible for hair loss in individuals with alopecia areata (AA), an auto-immune disease which occurs when the immune system wrongly attacks the hair follicles resulting in hair loss, medical researchers conducted a trial on a drug that could potentially cure the condition.

For the trial involving three patients with alopecia baldness, the researchers found that the pill fully restored the hair of the subjects; a breakthrough that scientists hope could pave way for a treatment that could help bald people regrow their hair.

Patients with alopecia areata often suffer from psychological and emotional distress. Rod Sinclair, a dermatologist from Melbourne, said that the condition could cause affected individuals, teenagers in particular, to become self-conscious and socially withdrawn. A report by Sinclair, which was published in the Medical Journal of Australia in 2012, also revealed of teenagers with alopecia areata attempting to commit suicide

“We’ve only begun testing the drug in patients, but if the drug continues to be successful and safe, it will have a dramatic positive impact on the lives of people with this disease,” said Raphael Clynes, from Columbia University Medical Center in New York, who led the study published in the journal Nature Medicine on Aug. 17.

The trial was conducted following tests on mice that used two new drugs that belong to a class of medicine known as JAK inhibitors, ruxolitinib, which is approved for use in the U.S and E.U as treatment for patients with a form of bone marrow cancer, and tofacitinib, which is FDA- approved for treatment of rheumatoid arthritis. In the experiments conducted on mice, both ruxolitinib and tofacitinib fully restored the hair of mice with alopecia in just 12 weeks.

For the human trial, the researchers used ruxolitinib for patients who have moderate to severe alopecia areata with over 30 percent hair loss. Within four to five months after starting the treatment, the researchers reported that all of the three patients have restored their hair growth. The T-cells responsible for destroying the hair follicles also disappeared from the patients’ scalp.

“Notably, three patients treated with oral ruxolitinib, an inhibitor of JAK1 and JAK2, achieved near-complete hair regrowth within 5 months of treatment, suggesting the potential clinical utility of JAK inhibition in human AA,” Clynes and colleagues reported.


 

 

With the new drug, patients with alopecia areata-related hair loss saw their hair fully restored after just five months of treatment (right)|

Alopecia areata is an autoimmune disease that causes hair loss for more than 6.5 million people in the US. Now, researchers havediscovered that a drug already approved by the Food and Drug Administration for treatment of a rare bone marrow disease – ruxolitinib – could restore hair growth in these patients.

The research team, led by Dr. Raphael Clynes and Angela M. Christiano of Columbia University Medical Center (CUMC), recentlypublished the initial findings of their ongoing clinical trial in the journal Nature Medicine.

“We’ve only begun testing the drug in patients, but if the drug continues to be successful and safe, it will have a dramatic positive impact on the lives of people with this disease,” says Dr. Clynes.

Alopecia areata is a disease whereby the immune system attacks hair follicles – the parts of the skin from which hair grows. The majority of people with this disease experience bald patches over their head, face and body, although the condition can cause total hair loss in some cases. Alopecia areata is notoriously difficult to treat and the resulting hair loss is often permanent.

It is unclear exactly what causes the disease, but this latest study may shed some light, as well as offer a potential treatment.

FDA-approved drugs ‘fully restored hair in mice within 12 weeks’

Four years ago, the CUMC team conducted a study of more than 1,000 patients with alopecia areata. Their findings indicated that hair follicles send a “danger signal” to immune cells, which encourages them to launch an attack on the follicles.

The researchers investigated this further by studying mice with the disease. By tracing the danger signal backwards, they identified a certain set of T cells responsible for attacking hair follicles.

Through further research into cells of both mice and patients with the disease, the team pinpointed several immune pathways through which these T cells launch their attack. These pathways, the researchers say, can be targeted by a class of drugs known as JAK inhibitors.

The researchers tested two JAK inhibitors already approved by the Food and Drug Administration (FDA) – ruxolitinib (approved for the treatment of myelofibrosis, a rare bone marrow disease) and tofacitinib (approved for the treatment of rheumatoid arthritis) – on mice with alopecia areata that had severe hair loss from the disease.

These drugs, the researchers say, fully restored the rodents’ hair within 12 weeks. Furthermore, this hair regrowth lasted for months after treatment had ceased.

Ruxolitinib restored patients’ hair within 4-5 months

In this latest study, the researchers report on the findings of a small, open-label clinical trial of ruxolitinib on patients with moderate-to-severe alopecia areata, defined as having more than 30 percent hair loss.

Early results of the trial revealed that in three of the participants, hair growth was fully restored within 4-5 months of treatment initiation. Furthermore, the T cells that attack the hair follicles were no longer present in the participants’ scalps.

Dr. Clynes says that although further testing is needed to determine whether ruxolitinib can be used for patients with alopecia areata, the findings so far are “exciting news” for those with the disease.

“There are few tools in the arsenal for the treatment of alopecia areata that have any demonstrated efficacy,” explains Dr. David Bickers, of the Department of Dermatology at CUMC. “This is a major step forward in improving the standard of care for patients suffering from this devastating disease.”

Earlier this year, researchers from Yale University published a study revealing how tofacitinib helped a man with alopecia areata grow a full head of hair.

Preventing Hair Loss through Ayurveda

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For thousands of years, men and women of all countries and races have shared the tragedy of pre-mature hair loss.

According to Ayurveda, the hair is derived either as a by-product or produced as a breakdown product of Asthi (bone tissue). Any disturbance in this tissue metabolism, which very much depends on the digestive fire, can affect the health of the hair. To a certain extent, the quality of hair depends on the body constitution.

The reason for hair loss is a subject that no two doctors, seem to agree on and everyone seems to have their own opinion on the subject. The major causes of hairfall are hormonal, nutritional deficiencies and complication to other diseases and medications. Hormone related hair fall may also result from an increased sensitivity of hair follicles to male hormones or due to greater number of male hormone receptors attached to hair follicles. This is the component that is inherited through the genes — termed as Pitta constitution.

 

According to Ayurveda, excess of Pitta dosha in the body is increased by hot climatic conditions, excessive intake of spicy, salty and sour food, hot and sharp food, tea, coffee, alcohol, meats and excessive smoking. Eating too much fried, oily, greasy, and acidic foods also aggravates Pitta. Pitta balancing herbs (Eg: Shatavari —Asparagus) and vegetables which improves the quality of Asthi dhathu (Eg: bitter vegetables) are effective in treating hair fall.

There are a number of other causes for hair fall like acute illness, high stress, and thyroid imbalance, certain drugs, sudden weight loss and high fever.

The first step is to locate the root cause in your diet or lifestyle that may be increasing the Pitta dosha. Once you locate it, try to give up or at least reduce the diet, habit, or activity responsible for increasing Pitta. Internal use of Ayurvedic medicines like Thikthakam kashayam, Thikthakam ghritham as per medical advice are effective to correct the metabolism. Ayurvedic general tonics like Narasimha rasayanam, Chyavana prasam are effective for improving hair growth. In alopecia, due to systemic diseases, treatment of the same is also required.

General recommendations and tips to maintain the results are some of the following:
– A high protein and an iron rich diet is recommended for hair loss. An adequate intake of raw vegetables, fresh fruits, salads, green leafy vegetables should be included in the diet on a regular basis. – Use a natural shampoo to clean the hair. Amla (embilica officinalis), Shikakai (Acacia concinna) are very good for washing the hair. – Oiling and massaging of scalp is very beneficial for stopping the hair loss. Use coconut oil at least three times in a week. Certain medicated oils like Neelibhringadi oil, Kunthala kanthi oil, Kanjunnyadi oil are very useful. Put oil on the scalp, and massage gently in the roots of the hair.
– The person should maintain a regular bowel movement everyday. In case of constipation, a mild natural laxative can be taken. Triphala is very useful. – Regular physical exercise is very beneficial as it helps in balancing the aggravated doshas. – Rub your scalp after washing the hair. It increases the blood circulation, and activates the sebaceous glands. – A mixture of lettuce and spinach juice is good to drink to induce hair growth. The juice of carrot, and lettuce juice is also good to take. – Applying juice of green coriander leaves on the head is also good. – Washing the hair with a paste of cooked green gram and fenugreek (methi) two to three times a week, is also good. – A paste of licorice made by grinding it in milk can be applied in the bald patches. – The seeds of fenugreek is soaked in coconut oil and kept under direct sunrays for seven days and applied to the scalp, which prevents hair loss. – Traditional therapies like Dhara, Abhyangam, Thala pothichil, Nasya shows excellent effects.

(Inputs by Dr V L Shyam MD, MPhil)

 


 

Preventing Hair Loss through Ayurveda

http://www.jiva.com/ayurveda/about-ayurveda/100.html

Hair is the most important cosmetic addition to our appearance. Since healthy hair is a sign of a healthy body, it is important for us to keep our hair silky, shiny and thick.

Everybody has experiences of hair loss sometime or the other in their lives. In medical terms, loss of hair is known as ‘alopecia’. Alopecia may be a sign of some underlying disease. It costs our beauty and thereby brings in a set of depressing emotions.

In this article, we shall discuss the causes and remedies of hair loss in the light of the Indian Ayurvedic system of medicine. To know the causes of hair fall, it is very essential to know the structure of the hair and its normal growth cycle.

Structure of Hair
The hair on our scalp can be divided into two parts—the root and the shaft. The root of the hair is inside the skin (epidermis) of the scalp. Each hair root is surrounded by a pouch-like structure called follicle. The base of the hair root is in the shape of a bulb. This bulb is indented by capillaries and nerve fibres. Cell division takes place in the centre of the bulb and the newly divided hair cells push the previous cells up. The cells which move upwards die slowly forming the hard hair shaft.

The hair shaft has three layers—cuticle, medulla and cortex. Cuticle is the transparent outer layer which protects the other two inner layers. A healthy cuticle gives a shiny appearance to the hair whereas an unhealthy cuticle lends it a lifeless look.

Medulla is the innermost layer composed of large cells. Cortex is the layer between the cuticle and the medulla which contains pigments and keratin. Cortex determines the bulk and strength of the hair.

The hair follicle contains oil-secreting glands which make the hair look shiny. Stress and illness diminish the secretion of oil and pigments, causing the graying of hair.

According to Ayurveda, hair is considered to be a tissue which uses the same nutrients as the bones and is formed as a bi-product of the bone tissue.

Normal Cycle of Hair Growth
About 10% of the hair on the scalp is in a resting phase at any given time. The resting hair falls after 2 to 3 months and new hair starts to grow in its place. The growing phase continues for around 2.25 to 6 yrs. During this phase each hair grows approximately 1 cm per month. At any given time about 90% of the hair on the scalp is in the growing phase.

Normally, the dead hair decays at the rate of 70 to 80 strands per day. The rate of decay increases in the rainy and damp season. A rate of fall or decay greater than this is considered alarming and such a situation may be termed as hair loss.

Ayurvedic Classification of Hair
Ayurveda has classified the hair type according to the three basic body types—vata, pitta and kapha. According to Ayurveda, people falling under any of these body types have different hair features as per their doshas. Let us discuss the hair properties of people with respect to vata, pitta and kaphaconstitutions.

Hair of People with Vata Constitution
The hair of people with predominantly vata type of constitution is generally dark, coarse, wiry, inky, and frizzy. Such type of hair gets tangled easily and is prone to be dull with split ends. Such hair also has the possibility of dandruff infection.

Hair of People with Pitta Constitution
The hair of people with predominantly pitta type of constitution is generally brown, blonde, light, fine and silky. People with pitta constitution face problems like premature graying of hair and premature baldness. Such hair with a dominance of pitta tends to become oily particularly in hot and dry weather. This situation also leads to the dullness of hair.

Hair of People with Kapha Constitution
The hair of people with predominantly kapha type of constitution are generally dark or light, thick, heavy, wavy, and slightly oily. The hair of people with kapha constitution is lustrous.

Causes of Hair Loss
Hair is nourished by the nutrient plasma, which is produced by the metabolic processing of the food we consume. The healthy nutrient plasma is responsible for the nourishment of the hair. According to Ayurveda, excess of pitta dosha (heat) in the body is the chief cause of hair problems. There are various other reasons for hair loss as mentioned below:

  1. Hormonal imbalance in men and women is an important cause of hair loss. In men, a high concentration of dihydrotestosterone (DHT) in hair follicles causes hair fall. In women, hormonal imbalances both during pregnancy and after delivery cause hair fall.

  2. High amount of sebum in the scalp clogs the pores of the scalp and prevents nutrients from reaching the hair follicle, resulting in hair loss.

  3. Inadequate nutrition or unhealthy diet also causes hair fall.

  4. Stress, worry, lack of sleep, and anxiety too cause hair fall.

  5. Long-standing diseases like typhoid, viral infections, anaemia, surgery, etc. cause general debility which leads to hair fall.

  6. Some medicines like birth-control pills, anti-depressants, etc., including those used for gout, during chemotherapy against cancer, etc. cause hair fall.

  7. Diseases like lupus and diabetes also cause hair fall.

  8. Tying hair tightly pulls the hair from the follicles and cause traction alopecia.

  9. Heredity is also responsible for hair fall.

  10. Dandruff or fungal infection of scalp causes hair fall.

  11. Accumulation of dirt on scalp causes blocking of pores and weakens hair roots. This leads to hair fall.

Hair Loss Remedies
Hair loss, in general, can be stopped or reversed at home by taking some simple steps. However, in case of chronic alopecia, expert guidance is required which has been described in the ‘Treatment’ section of this article.

  1. The first step is to locate the root cause in your diet or lifestyle that is causing the pitta dosha. Once you locate it, try to give up or at least reduce the diet, habit or activity responsible for increasing pitta.

  2. Always use a natural shampoo or soap (without too many chemicals) to clean the hair.

  3. Oiling and massaging of the scalp is highly beneficial in preventing hair loss. Use coconut oil or mustard oil at least three times in a week. Certain medicated oils like Mahabhringraj oil, Amlaoil, and Arnica oil are also very useful.

  4. Ensure regular bowel movement everyday. In case of constipation, a mild natural laxative may be taken. One teaspoonful of Triphala powder can be taken at bedtime with warm water.

  5. Rub your scalp vigourously after washing the hair. It increases the blood circulation and activates the sebaceous glands.

  6. A paste of licorice made by grinding it in milk can be applied in the bald patches. It induces hair growth. A paste of the seeds of lemon and black pepper may also be applied on the bald patches.

  7. Consume raw vegetables, fresh fruits, salads, and green leafy vegetables regularly.

  8. Use relaxing techniques such as yoga, pranayama, etc. to overcome stress, anxiety and sleeplessness.

  9. Avoid hairstyles which pull the hair and consequently damage it.

Diet Regimen
Ayurveda requires you to maintain some simple diet regimens. These can no doubt be easily followed.
Do’s: Dont’s:

High protein diet like milk, buttermilk, soya bean, cheese, ghee, butter should be taken. Seeds, nuts and grains should also be taken on a regular basis. Seasonal fruits and vegetables should be consumed in sufficient amounts. Sprouts made fromMoong or Chana dal are also recommended. In addition, taking food items that cool the body and living in a cool climate (especially in the summer) is very beneficial.

One should avoid pitta-aggravating diet such as fried, spicy and sour foods. Excess use of yogurt, pickles, tea, coffee, alcohol and non-vegetarian foods also increasespitta. Smoking should be avoided. White flour/white sugar products should be avoided. Junk foods, fast foods, or foods that contain artificial colours, flavours and preservatives should not be consumed regularly.

 

 


 

http://www.alopeciacure.com/groupd.html

http://www.ayurvedahaircare.in/

http://www.stylecraze.com/articles/10-effective-ayurvedic-tips-for-hair-growth/

https://sheeltalumhairoil.wordpress.com/

http://www.indiastudychannel.com/experts/25233-What-best-treatment-available-for-Hair.aspx

 

Stem Cell-based Baldness Cure One Step Closer | Beyond the Dish

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Stem Cell Consultant

Stem Cell-based Baldness Cure One Step Closer

http://www.mensfitness.com/sites/mensfitness.com/files/imagecache/node_page_image/article_images/male-pattern-baldness-main_0.jpg

January 28, 2014 – by mburatov

Scientists might be able to offer people with less that optimal amounts of hair new hope when it comes to reversing baldness. Researchers from the University of Pennsylvania say they’ve moved closer to using stem cells to treat thinning hair — at least in mice.

This group said that the use of stem cells to regenerate missing or dying hair follicles is considered a potential way to reverse hair loss. However, the technology did not exist to generate adequate numbers of hair-follicle-generating stem cells.

But new findings indicate that this may now be achievable. “This is the first time anyone has made scalable amounts of epithelial stem cells that are capable of generating the epithelial component of hair follicles,” Dr. Xiaowei Xu, an associate professor of dermatology at Penn’s Perelman School of Medicine, said in a university…

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Olive Oil is Effective to Cure Baldness and Regrow Your Hair

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Home Remedies For Hair Growth

Olive-Oil

Various kinds of hair growth products outstanding and flooding the market today. But nevertheless, olive oil remains one of the favorites and is believed to grow hair and can overcome hair loss. Perhaps this is because the oil has been used from generation to generation and so it became very popular for most people.

Olive oil being one of the essential oils are widely used for various kinds of diseases, even for most of Muslim, Christian and Judaism, olive oil is the main drug and is considered sacred oils to treat various diseases. Olive oil is very popular and began to be applied in the Middle Ages in Europe and in the Mediterranean. Italy and Spain are the two main country olive oil producing and they have a high quality on their olive oil products.

How to Use Olive Oil for Grow Healthy Hair

Olive oil can repair damaged hair…

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Early Hair Loss May Put Men At Risk For Prostate Cancer

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Dr. Neil Baum's Urology Blog

Men Who Experience Balding In Their 20s May Be At Risk For Developing Prostate Cancer.

CNN (2/16, Falco) in its “The Chart” blog reports, “Men who start losing their hair at 20 may be twice as likely to get prostate cancer later in life,” according to a study in the Annals of Oncology. The researchers studied “388 men with prostate cancer and 281 healthy men and asked how bald they were at age 20, 30 and 40.” They found that when a “man’s hair began to thin in his 30s or 40s, the risk for prostate cancer did not go up.” But any “type of balding [at age 20] is a risk factor for prostate cancer,” suggested lead author Dr. Michael Yassa of the Maisonneuve-Rosemont Hospital in Montreal, Canada.

Bloomberg News (2/16, Von Schaper) adds that early hair loss was associated with prostate cancer risk, but not with “earlier onset…

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Hairloss research in bed with Big Pharma

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Good Study

Body image, critical psychology and other stuff

It’s not only hair loss support websites in bed with hair loss pharmaceuticals (see previous post). It seems hair loss research is also. So far, and I haven’t been looking hard, I’ve found 9 studies either funded by a hair loss pharmaceutical company or where one of the authors of the study are professionally employed by them:

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Baldness Breakthroughs :

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Baldness breakthrough as scientists grow cells that sprout human hair for the first time

  • Scientists have found a way of cloning the cells that contain the ‘instruction manual’ for growing new hair
  • The lab-grown cells sprout hair when put back into human skin
  • Treatment could be cheaper than hair transplants currently are

By Fiona Macrae Science Correspondent

PUBLISHED: 16:37 GMT, 21 October 2013 | UPDATED: 00:54 GMT, 22 October 2013

Baldness could soon be nothing more than a bad memory, thanks to a breakthrough by British scientists.

In research that could ‘transform’ the treatment of hair loss, they have found a way of cloning the tiny cells that contain the ‘instruction book’ for growing new hair.

In a world first, they have shown that when these lab-grown cells are put back into human skin, they sprout hair.

Although the work is at an early stage, the scientists from Durham University in the UK and Columbia University in the US, say it represents a real breakthrough in treating the hair loss that blights millions of men and women.

Options at the moment are limited to drugs and hair transplants.  But drugs can have side-effects and hair transplants simply work with what is there, by redistributing existing hair.

In contrast, the new technique should actually boost the number of hairs on the head.

Columbia University researcher Dr Angela Christiano, who suffers from alopecia, in which clumps of hair fall out, said the work ‘has the potential to transform the medical treatment of hair loss’.

The team began by taking strips of human hair and extracting tiny cells called dermal papillae.

Found in clumps at the base of a hair, these cells contain the ‘instruction book’ for the growth of new hair.

The scientists then cloned the cells in a dish, until they had multiple copies of each one.

22R_BALDNESS_CURE (Read-Only).jpg

Other scientists have done this before but then failed to get the lab-grown cells to sprout hair when put back into skin.

The UK-US team got over this hurdle by turning the dish of cells upside down, to encourage them to form into the clumps found in nature.

The clumps were then transplanted into human skin that had been grafted on the backs of mice.

Once there, they sent out the instructions needed for new hairs to grow.

Cells from all seven human donors sprouted fledgling hairs and, in two or three cases, the tufts broke through the skin, the journal Proceedings of the National Academy of Sciences reports.

The new hairs were white but Durham researcher Colin Jahoda  says it should possible to produce coloured hair in future.

Starting with a sample of a person’s own cells should also mean that any new hair is a good match in terms of texture and curliness.

Professor Jahoda said: ‘There are a lot of technical hurdles to cross before using it as a cosmetic treatment but this is a very important step forward.’

It is hoped that the first human trials will start soon and that men and women will both eventually benefit from the new treatment.

It is too early to say exactly how much it will cost but it could be cheaper than hair transplants which can cost up to £30,000 per patient, although the average price is £6,000 to £10,000.

Burns victims could also benefit, as replacement skin that is studded with hairs should be more functional than a completely smooth covering.

Although baldness is usually thought of as a male problem, some eight million British women are losing their hair.

Greg Williams, a hair transplant surgeon at the Farjo Hair Institute in London’ s Harley Street, said hair loss and thinning can be particularly devastating for women.

‘I can’t put enough emphasis on the fact that a woman’s hair is central to her psychological wellbeing, the confidence she has in her appearance and her sense of identity.’

Dr Williams said that hair transplants are often less suitable for women and the new technique ‘if it come to fruition, could be very, very beneficial for a lot of people’.

Prof Sheila MacNeil, of the University of Sheffield, said: ‘This is ground-breaking work.’

But Dr David Fenton of the British Association of Dermatologists warned that any treatment is still years away.

He said: ‘It is something for researchers to be excited about but not something that consumers should hold their breath for.’

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A CURE for baldness is a step closer after scientists developed a pioneering technique which grows new hair.

Using a patient’s own cells to regenerate follicles, it offers hope to 7.4 million Britons who, like football star Wayne Rooney, face expensive treatments and transplants to restore their hair.Researchers say it could also help women too as well as burns victims.Experts at the University of Durham and Columbia University Medical Center in New York say clinical trials could begin “in the near future”.

The team showed it was possible to regenerate follicles that could sprout new hair.

They grow from clusters of cells called dermal papillae which trigger new growth. The gradual death of these cells causes baldness.

The scientists harvested the cells from seven human donors, cloned them in a laboratory, and transplanted them into human skin grafted onto mice.

In five cases, the transplants resulted in new hair growth that lasted at least six weeks.

DNA analysis confirmed the new follicles were a genetic match to the donors.

It would be good news for younger men such as England footballer Rooney who underwent a nine-hour hair transplant this summer at London’s Harley Street Hair Clinic.

The surgery was a top-up treatment following 27-year-old Rooney’s initial transplant in 2011

Professor Angela Christiano, from Columbia University Medical Center, said: “Current hair-loss medications tend to slow the loss of hair follicles or potentially stimulate the growth of existing hairs, but they do not create new hair follicles.“Neither do conventional hair transplants, which relocate a set number of hairs from the back of the scalp to the front.“Our method has the potential to grow new follicles using a patient’s own cells.

“This could greatly expand hair restoration surgery to women and to younger patients.

“Now it is largely restricted to the treatment of male-pattern baldness in patients with stable disease.”

The research develops earlier work by Professor Colin Jahoda at the University of Durham, who co-led the new study which is published in the journal ­Proceedings of the National Academy of Sciences.

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For the first time, scientists have shown that it is possible to renew follicles capable of sprouting human hair.The follicles grow naturally from clumps of cells called dermal papillae that play a pivotal role in hair growth.Scientists harvested dermal papillae from seven human donors, cloned them in the laboratory, and transplanted them into human skin grafted onto the backs of mice.

In five of the tests, the transplants resulted in new hair growth that lasted at least six weeks. DNA analysis confirmed that the new hair follicles were human and a genetic match to the donors.

Although the research is at an early state, the British and American team is confident clinical trials could begin “in the near future”.

Professor Angela Christiano, from Columbia University Medical Centre in New York, said: “Current hair-loss medications tend to slow the loss of hair follicles or potentially stimulate the growth of existing hairs, but they do not create new hair follicles. Neither do conventional hair transplants, which relocate a set number of hairs from the back of the scalp to the front.

“Our method, in contrast, has the potential to actually grow new follicles using a patient’s own cells. This could greatly expand the utility of hair restoration surgery to women and to younger patients – now it is largely restricted to the treatment of male-pattern baldness in patients with stable disease.”

Dermal papillae are small cells found at the base of hair follicles. The research develops earlier work led by Professor Colin Jahoda at the University of Durham showing that in rodents dermal papillae could easily be harvested and transplanted back into the skin.

In rodents, the transplanted cells tended to clump together spontaneously and reprogramme the recipient’s skin to grow new hair follicles.

The new research followed the lessons learned in rodents by encouraging human cells to clump together in the same way.

“Dermal papilla cells give rise to hair follicles, and the notion of cloning hair follicles using inductive dermal papilla cells has been around for 40 years or so,” said Prof Jahoda, who co-led the research published in the journal Proceedings of the National Academy of Sciences.

“However, once the dermal papilla cells are put into conventional, two-dimensional tissue culture, they revert to basic skin cells and lose their ability to produce hair follicles. So we were faced with a Catch-22: how to expand a sufficiently large number of cells for hair regeneration while retaining their inductive properties.”

The technique may offer new hope to women as well as men who suffer from baldness, say the scientists. It also raises the prospect of new treatments for burns victims.

“About 90% of women with hair loss are not strong candidates for hair transplantation surgery because of insufficient donor hair,” said Prof Christiano. “This method offers the possibility of inducing large numbers of hair follicles or rejuvenating existing hair follicles, starting with cells grown from just a few hundred donor hairs. It could make hair transplantation available to individuals with a limited number of follicles, including those with female-pattern hair loss, scarring alopecia, and hair loss due to burns.”

Prof Jahoda said more work was needed to explore the properties of hair generated by newly grown follicles, and the interaction between transplanted dermal papillae and host cells.

He added: “Ultimately we think that this study is an important step toward the goal of creating a replacement skin that contains hair follicles for use with, for example, burn patients.”

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A breakthrough technique that can generate human hair growth shows promise for treating baldness in men and women, a new study suggests.

“If it works in humans, it actually opens up the possibility of hair restoration for many more patients than are currently available,” study co-leader Angela Christiano, a dermatology professor at Columbia University Medical Center, told NBC News.

In the study, Christiano and colleagues took dermal papillae — cells inside the base of human hair follicles — from seven donors and cloned the cells in tissue culture. After a few days, the cells were transplanted onto human skin that had been grafted onto the backs of mice.

The transplants resulted in new hair growth lasting at least six weeks in five of the seven tests, according to the findings. DNA analysis confirmed that the new hair follicles genetically matched the human donors.

The research is in its early stages, so it may be years before this science makes its way to the marketplace to help men and women with notable hair loss by age 60.

The study was published Monday in the online edition of the Proceedings of the National Academy of Sciences.

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Scientists say they have moved a step closer to banishing bald spots and reversing receding hairlines after human hair was grown in the laboratory.

A joint UK and US team was able to create new hairs from tissue samples.

Far more research is needed, but the group said its technique had the “potential to transform” the treatment of hair loss.

The study results were published in the journal Proceedings of the National Academy of Sciences.

There are baldness therapies including drugs to slow the loss of hairs, and transplants, which move hair from the back of the head to cover bald spots.

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“Yeah I think it [baldness] will eventually be treatable, absolutely.”

Prof Colin Jahoda, Durham University

The scientists at the University of Durham, in the UK, and Columbia University Medical Centre, in the US, were trying to actually grow new hairs.

Their plan was to start with material taken from the base of a hair and use it to grow many new hairs.

Tricky feat

But human hair has been tricky to grow despite successes in animal studies.

Whenever human tissue was taken from the dermal papillae, the cells which form the base of each hair follicle, the cells would transform into skin instead of growing new hairs.

However, the group found that by clumping the cells together in “3D spheroids” they would keep their hairy identity.

Tissue was taken from seven people and grown in 3D spheroids. These were then transplanted into human skin which had been grafted on to the backs of mice.

Hair follicle Cells were taken from the base of a follicle and used to grow new hairs

After six weeks, new hair follicles formed in five out of the seven cases and some new tiny hairs began to form.

Prof Colin Jahoda, from Durham University, told the BBC a cure for baldness was possible but it was too soon for men to be hanging up the toupee.

“It’s closer, but it’s still some way away because in terms of what people want cosmetically they’re looking for re-growth of hair that’s the same shape, the same size, as long as before, the same angle. Some of these are almost engineering solutions.

“Yeah I think it [baldness] will eventually be treatable, absolutely.”

He added: “It’s hard to say exactly how long that would take, but the fact that we’ve done it now should reawaken interest.”

Any future therapy would involve transplanting cells which have been grown in the laboratory so safety is a concern.

There would be a risk of infection and the cells could become abnormal, or even cancerous, while being grown.

Baldness cures may not be the first application of the research. Prof Jahoda believes the findings will be used to improve the quality of skin grafts used after severe burns.

Prof Angela Christiano, from Columbia University, said: “This approach has the potential to transform the medical treatment of hair loss.

“Current hair-loss medications tend to slow the loss of hair follicles or potentially stimulate the growth of existing hairs, but they do not create new hair follicles.

“Our method, in contrast, has the potential to actually grow new follicles using a patient’s own cells.”

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Clue to male baldness discovered

A biological clue to male baldness has been discovered, raising the prospect of a treatment to stop or even reverse thinning hair.

In studies of bald men and laboratory mice, US scientists pinpointed a protein that triggers hair loss.

Drugs that target the pathway are already in development, they report in the journal Science Translational Medicine.

The research could lead to a cream to treat baldness.

Most men start to go bald in middle age, with about 80% of men having some hair loss by the age of 70.

The male sex hormone testosterone plays a key role, as do genetic factors. They cause the hair follicles to shrink, eventually becoming so small that they are invisible, leading to the appearance of baldness.

Reverse balding?

Now, researchers at the University of Pennsylvania have analysed which genes are switched on when men start to go bald.

They found levels of a key protein called prostaglandin D synthase are elevated in the cells of hair follicles located in bald patches on the scalp, but not in hairy areas.

Mice bred to have high levels of the protein went completely bald, while transplanted human hairs stopped growing when given the protein.

Prof George Cotsarelis, of the department of dermatology, who led the research, said: “Essentially we showed that prostaglandin protein was elevated in the bald scalp of men and that it inhibited hair growth. So we identified a target for treating male-pattern baldness.

“The next step would be to screen for compounds that affect this receptor and to also find out whether blocking that receptor would reverse balding or just prevent balding – a question that would take a while to figure out.”

The inhibition of hair growth is triggered when the protein binds to a receptor on the cells of hair follicles, said Prof Cotsarelis.

Several known drugs that target this pathway have already been identified, he added, including some that are in clinical trials.

The researchers say there is potential for developing a treatment that can be applied to the scalp to prevent baldness and possibly help hair regrow.

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Therapy uses platelet-rich plasma to treat hair loss

by RON CORNING / WFAA

WFAA

Posted on November 7, 2013 at 1:39 PM

DALLAS — There is no shortage of pills, creams, devices and procedures for men and women losing their hair.

Many carry only false hope of helping regrow hair. But, one local clinic is using a technique that’s working for men and women.

Shala Allen was diagnosed with cancer six years ago and braced for the hair loss.

“It was just awful to lose your hair,” she said. “It’s humiliating for you.”

And, like so many other cancer survivors, she was left with a lasting, noticeable reminder of her long fought battle. Her hair never grew back.

“Probably about four years and I would wear wigs and caps so people could not see,” Allen said.

But, then she heard about PRP. A simple process in which your blood is drawn and put into a centrifuge. The platelet-rich plasma, or PRP, is separated and injected into the scalp.

Long used to help promote healing in sports medicine, Clinician Bill Moore at Advanced Skin Fitness was the first in Dallas to use PRP for hair replacement.

But, Dr. Abraham Armani cautions that not everyone is a candidate.

“It’s sort of like fertilizer for a lawn,” Armani said. “[It’s] not going to grow new grass … It’s not a cure for baldness; it’s another effective method to have thicker healthier hair.

Allen said it worked for her.

“Within a month, I started to see some fuzz,” she said. “I was very excited about that.”

The results have been good enough for Allen to encourage the treatment for others.

“I would say don’t hesitate,” she said. “Don’t hesitate to do this for yourself.’

Ideal candidates are younger man and women with newly thinning hair and can serve as an alternative for Propecia patients who experience adverse side effect.

The therapy costs about $850 per treatment.

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Neograft a great solution for hair loss

By Robert Hunter, MD, Board Certified Obstetrics and Gynecology

Question: Is there anything I can do for hair loss?
Answer: Hair loss is a far too common problem, equally affecting both men and women. It is a stressful condition because it is visible to others, and negatively impacts self esteem.
Typically, after underlying medical conditions have been ruled out, patients are left frustrated without a solution for their hair loss. Fortunately, there are many treatments available to combat hair loss, including hair transplantation.
Historically, hair transplants for women were not an option, and for men it was considered a last resort because of scarring, down time, and unnatural hairlines.
Now, with the advent Neograft — an automated hair transplant device — transplantation is a viable option for both men and women. This technology allows for extraction of individual hair follicles from the back of the head that are genetically impervious to falling out. These follicles are then re-implanted in areas of hair loss. This process is discreet and natural looking, avoiding past problems of unsightly scars and obvious evidence of a transplant, even immediately following the procedure.
Hair transplantation with Neograft is typically completed in one day and requires minimal recovery time. This revolutionary safe and effective procedure is now available as part of the comprehensive hair restoration program at MD Beauty Labs.


Dr. Robert L. Hunter is Board Certified in Obstetrics and Gynecology. He has a private gynecology practice and also works with MD Beauty Labs in West Palm Beach. He educates medical students and is also honored to participate as a guest lecturer for the Sex Therapy Postgraduate Training Institute.

CONTACT INFORMATION

MD Beauty Labs Medical Spa and Wellness Center

320 S. Quadrille Blvd.; West Palm Beach

(561) 655-6325

By Robert Hunter, MD, Board Certified Obstetrics and Gynecology

Question: Is there anything I can do for hair loss?
Answer: Hair loss is a far too common problem, equally affecting both men and women. It is a stressful condition because it is visible to others, and negatively impacts self esteem.
Typically, after underlying medical conditions have been ruled out, patients are left frustrated without a solution for their hair loss. Fortunately, there are many treatments available to combat hair loss, including hair transplantation.
Historically, hair transplants for women were not an option, and for men it was considered a last resort because of scarring, down time, and unnatural hairlines.
Now, with the advent Neograft — an automated hair transplant device — transplantation is a viable option for both men and women. This technology allows for extraction of individual hair follicles from the back of the head that are genetically impervious to falling out. These follicles are then re-implanted in areas of hair loss. This process is discreet and natural looking, avoiding past problems of unsightly scars and obvious evidence of a transplant, even immediately following the procedure.
Hair transplantation with Neograft is typically completed in one day and requires minimal recovery time. This revolutionary safe and effective procedure is now available as part of the comprehensive hair restoration program at MD Beauty Labs.


Dr. Robert L. Hunter is Board Certified in Obstetrics and Gynecology. He has a private gynecology practice and also works with MD Beauty Labs in West Palm Beach. He educates medical students and is also honored to participate as a guest lecturer for the Sex Therapy Postgraduate Training Institute.

CONTACT INFORMATION

MD Beauty Labs Medical Spa and Wellness Center

320 S. Quadrille Blvd.; West Palm Beach

(561) 655-6325

www.MDBeautyLabs.com

info@mdbeautylabs.com

 

Stem cell researchers from Durham University and Columbia University have discovered that it’s possible to regrow hair follicles in human skin. Even though it’s only been tested on mice, the researchers are confident that they’re taking the right steps towards developing a solution for alopecia and other forms of hair-loss.

Recently published in the Proceedings of the National Academy of Sciences, the researchers (including a Angela Christiano, who suffers from alopecia herself) took cells from donor hair follicles, called “dermal papillae,” and were able to grow new hair from the cells in a process called “neogenesis.”

Christiano said that the discovery ”has the potential to transform the medical treatment of hair loss,”  and offers ”the possibility of inducing large numbers of hair follicles or rejuvenating existing hair follicles, starting with cells grown from just a few hundred donor hairs.”

This marks the very first time science has been able to generate new hair growth; usually the neogenesis fails because the dermal papillae lose their ability to induce hair growth in a petri dish. Slap the cells onto some infant foreskins (post-circumcision) instead, and suddenly – hair growth galore! They then grafted the cells onto mice, and the hair growth continued.

Next up – grafting them onto bald people! (We can only assume).

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Is a thyroid condition causing your hair loss?

Believe it or not, you can tell a lot about a person’s health by looking at his or her hair.

We recently received this email from a viewer:

Hi Dr. Manny,
If you lose your hair from a thyroid condition, will it grow back after treatment?
Thanks,
Dulce

Hair cells are some of the fastest growing cells in the body. So when your body is under stress from illness, hair cells can shut down to redirect the energy elsewhere to help heal what ails you.

According to the Academy of Dermatology, almost half of the American population experiences thinning hair by the age of 40, but people with certain thyroid conditions may start to lose their hair even earlier and more quickly.

“The good news is that your doctor can prescribe thyroid hormone medication to help your hair grow back,” said Dr. Jennifer Landa, chief medical officer for BodyLogicMD. “The first thing that you’ll notice is a slowing of the hair loss, and then the hair will start to grow back, and ultimately it will grow thicker and stronger.  But this can take several months.”

Landa added that if a patient has been on thyroid hormone medication for an extended period of time and is not seeing results, he or she should ask for a free T3 test – which measures for a specific thyroid hormone called triiodothyronine.

“Most medication that we get for thyroid is T4 (thyroxine), and most patients do very well on that,” she said. “But there are many patients that would benefit from the addition of some T3 into their thyroid hormone regimen to help them grow back hair longer and stronger.”

Do you have a health question for Dr. Manny? Please send it toDrManny@foxnews.com.

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Have researchers found a cure for balding?

By Dr. David B. Samadi

Published November 01, 2013

One of the hardest realizations you can come to as an adult is the fact that you’re getting older.  For many of us though, it doesn’t fully sink in until that exact moment when you look in the bathroom mirror and start to see your hair thinning.You feel like you are losing a little bit of yourself with each strand.

Every memory of combing your hair before picture day in school, shaving your head for summer swim meets, growing it long in winter to keep your head warm, are all fading.  One truth is all that matters now, and that is that you will never have what you once did, and you will forever be looking in the mirror to see how much is gone.

In the United States alone, about 35 million men and 21 million women are currently experiencing hair loss.  Mistakenly thought to be a strictly male disease, women actually make up forty percent of American hair-loss sufferers.

Could a new study just released by Columbia University Medical Center in New York City and the University of Durham in England hold the key to curing baldness? Not quite yet, but researchers claim this discovery could “revolutionize” the medical treatment of hair loss.

Scientists in the U.S. and Britain may have come much closer to finding a cure for baldness.  For the first time they have generated new hair follicles that grow human hair.  The method involved harvesting cells from the base of a human hair follicle, or dermal papillae, and cloning them in the laboratory.  They then implanted these cloned cells into human skin grafted, or attached, to the back of a mouse. The dermal papillae cells were taken from seven different human donors.  Of the seven cases, five of the mice grew new hair on the grafted skin.

The same technique still needs to be translated into human trials, but there is hope for revolutionary treatment for hair loss in the not so distant future.  If this method works in human trials, there are many potential benefits, such as growing hair follicles for traditional transplantation, skin grafts for burn victims, and creating new hair follicles by direct injection of cells into the scalp.  This is especially beneficial for women, who historically have had a more difficult time responding to transplantation, and other medical treatments for balding.

Although researchers have not been able to reverse hair loss, or stop the physical process of balding, this breakthrough could mean a remedy for hair loss in the form of regenerative medicine, the body using its own cells to restore hair, at least. New research will also allow drug companies to test any number of compounds on growing hair follicles.  This advance could help in the discovery of new drug therapies to combat baldness.

 

Dr. David B. Samadi is the Chairman of the Department of Urology and Chief of Robotic Surgery at Lennox Hill Hospital in New York City. He is a board-certified urologist, specializing in the diagnosis and treatment of urological disease, with a focus on robotic prostate cancer treatments. To learn more please visit his websitesRoboticOncology.com and SMART-surgery.com. Find Dr. Samadi on Facebook.

 

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Hair Cycle

Posted on

Normal Hair Cycle Hair Transplant

Hair growth, just like all the other functions of the human body also has a normal cycle. If
something unnatural occurs such as any disease or perhaps a sudden event that interrupts the cycle, it definitely affects the hair growth.

Hair Growth Cycle

Hair loss and re-growth can be divided into three phases:-

  • The growing cycle
  • The resting cycle
  • The shedding cycle

Every phase has a specific duration and place in the cycle. Every cycle is different and unique to the hair follicles because every follicle operates individually from the other follicles. Remember, it’s the hormones which control and keep up the normal hair growth cycle.

Although every cycle is different but there are certain similarities which you can find in one
cycle to the other.

hair img Hair Loss

Hair Growth Stages

The First Phase

As the phrase “The growing phase” suggests, it’s a phase where new hair grows and allows the lengthening of the new hair. It’s also known as the anagen phase. In this phase, hair is born at the root. When it comes to the maintenance of the new hair, it is done through the blood vessels, which helps the hair to nourish. It’s a phase which lasts around two-eight years. And, the result is complete hair growth.

The Second Phase

In the resting phase, hair strands are maintained properly. During this phase, the hair follicles receive a lot of nourishment and it’s also the time of preparation of hair strand shedding. Hair follicles usually last for an average of 60-180 days after which the follicles get degraded and then it’s time for the growth of new hair. Then, it’s the last phase which is known as “The shedding phase”.

The Third Phase

It’s the shortest phase. In this phase, old hair strands are released because of the growth of new hair. After the completion of this phase, the same cycle starts i.e. the hair follicles again enters the growth phase. In this phase, it’s around fifty to hundred hair strands which fall during this phase. This phase is associated with baldness.

Hair loss – When does it occur to men?

A majority of the men tend to undergo male pattern baldness in the early stage of their life. For some men, it could even be as early as 17 or 18. This can have an incredibly bad effect on your overall personality and lifestyle. On the other hand, baldness or hair loss can also happen in the later stage of one’s life – in their 30s or 40s.

When an individual starts noticing some degree of hair loss on his head, chances are that he’ll try a number of methods for concealing his baldness. According to researches, MPB or male pattern baldness accounts of almost 90 percent of hair loss among men, with two-thirds of them losing a considerable amount of hair by the age of 35. Baldness or receding hairlines is inextricably related to a person’s personal and social life, often resulting in a lot of emotional and physical distress.

U-FUE or FUE does it leave scars or marks ?

Posted on Updated on

U-FUE or FUE does it leave scars or marks ?

FUE (Follicular Unit Extraction) Hair Transplant

Follicular Unit Extraction (FUE) is a hair transplant technique in which follicular units are removed directly from the donor area. The grafts are then transplanted into areas where the patient desires more hair to create a natural looking hair line and/or add density to areas of thinning.
Follicular Unit Extraction is different from the traditional FUT hair replacement procedures in one key way: follicular units are extracted directly from the scalp in FUE whereas follicles are microscopically dissected from a strip that has already been removed in FUT.

How Follicular Unit Extraction is Performed

During the Follicular Unit Extraction or FUE hair transplant procedure, individual follicular unit grafts are excised one at a time using a tiny one millimeter in diameter (or less) instrument. The device is used to make a small circular incision in the skin around the follicular unit. The graft is then extracted directly from the scalp.
Typically the patient’s hair in the donor area where these grafts are being removed is clipped, cut short or almost shaved so that the physician is able to optimally visualize the patient’s scalp.
The small opening left behind after the follicle unit is extracted heals in a few days. The tiny aperture contracts as it heals, making the resulting round scar less noticeable. The FUE patient typically ends up with many small light colored scars, which are normally not detectable to the naked eye once the patient’s hair grows out.

Best Candidates for Follicular Unit Extraction

The best candidates for FUE hair transplant procedure include:
  • Patients interested in a smaller size procedure (typically up to 1,000 grafts).
  • Patients with a limited donor supply.
  • Patients with limited scalp elasticity.
  • Patient who have had several FUT procedures and subsequently have a limited donor supply or limited scalp elasticity.
  • Patients who have a need or desire to wear their hair exceptionally short.
  • Patients who don’t mind closely clipping the donor area hair at the time of the procedure.

FUE Technique- Follicular Unit Extraction

FUE- The Cutting Edge Technology in Hair Transplantation

In FUE (Follicular Unit Extraction) method the hair roots are extracted by special tipped micro-engines under local anesthesia and transplanted into hairless areas by taking the natural hair grow angle and direction into account.
Today most of the hair transplantatiın operations are made through FUE technique. Since it is not a surgical operation the patients can decide easily and prefer this technique.

In FUE method the hair roots are extracted one by one and transplanted to hairless areas. Before the follicular extraction operation the hair on the donor area is shortened to 1 mm. Local anesthesia is applied on the area of extraction and transplantation. Micro motor tip approaches as to center the hair root and according to the development angle of the hair pricked into the skin and pulled back. The hair is cut in a cylinder shape together with the surrounding microscopic tissue. The follicular unit is being pulled gently by a micro forceps. This automated system which reduces the graft waste to minimum also reduces the operation time and increase the graft number in time unit. The collected follicular units are being placed into tiny holes on the hairless skin. Each follicular unit contains 2-3 follicules.

The features of FUE method are:
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• On the area where the grafts are extracted, the tissue is not extracted but only the related root cell is extracted.
• No cut and stitches on the extraction area. • Scars smaller than 06-07 mm occur on the extraction area which will be vanished in a couple of days and heal without any trace.
• Throughout this method, the grafts extracted from the nape can be used in hair transplantation as well as in eyebrow, mustache and beard transplantation.
• In one session, according to the condition of the donor area and according to the number of roots to be transplanted, 3.000 and 5.000 grafts can be extracted.
• Each graft contains 1-5 strands. 1 graft is considered as 2,5-3 strands.
• Depending on the gathered number of roots and baldness, it is possible to transplant 50-60 hair roots per square centimeters.
• Also less pain after the operation and the short recovery period are among the reasons to prefer this method.
Transplanted hair mostly be lost by the end of the first month and 2-3 months after the hair transplantation will begin growing again.
Becomes visible on 6th month. But takes the best form after completing the adaptation process in 1-1,5 years. Transplanted hair will not be lost since being extracted from an area coded for not being lost. The color and the characteristics of the hair will be the same since being extracted from the person oneself.

When carried out by a professional team, quite good results are taken in hair transplantation.
Lifelong growing hair changes the human appearance and also affects the psychology positively.
Hair transplantation is a scientific art since it requires visual quality and experience.
Self confidence increases as a result of naturally growing hair.

FUE (NO STITCHES)
(Also know by proprietary names such as DHI, FIT, CIT, FUSE, WOOD”S METHOD etc)In this method; the hair Roots (Follicular Units) are individually harvested one by one from the donor area by a micro punch device of 0.75 to 1 mm size. The wound is 1 mm or less in diameter and therefore heals rapidly with practically no visible scarring.
http://www.youtube.com/watch?v=GU3d0je6yZU
Recent advances have evolved this modern and stitch less method that eliminates the potential side effects occasionally seen in the conventional Strip Procedure because of the stitches in the donor area. This new method does not leave a linear scar on the back of the head and the wounds are tiny, there is less blood loss and heals faster compared to the strip method. The procedure is practically pain free post operatively.  Allows short hairstyle or buzz cut without showing up any linear scar. Final outcome is better. We use 0.75 to 1 mm micro punch with depth control and use the safest Lorenzo technique for extraction.
Unlike Strip method FUE does not expand the balding area due to stretch of the skin while stitching up the wound. It is better for the extraction of white hairs. It is ideal for tight scalp due to past surgery or fibrous skin where strip surgery can have donor area problems. FUE grafts are usually less bulky compared to strip grafts and therefore they require smaller size incisions for plantation and therefore less trauma is inflicted and more density can be packed.
Because of the nature of the procedure it is more expensive compared to strip procedure. For over 400 to 500 grafts usually you need to shave the entire donor area, which at times is a limitation for some people.
Unshaven FUE:
Well usually FUE needs shaving of the donor area. Because some people do not want to shave their head they cannot take regular FUE. But we have modified our techniques where we can now offer FUE even without shaving the entire donor area. This is a variant of FUE. This will not make it obvious to others that you have undergone such a procedure. This procedure is much more demanding and will take longer time to perform. We can harvest up to 1000 to 1200 grafts by this method. This procedure therefore costs more than the regular FUE procedure.http://www.youtube.com/watch?v=iwuFnA_O7eE

S
  1. FUE Donor Scars So Tiny Not Visible 1 Year After Hair Transplant 

    Apr 9, 2013 – Uploaded by jgdiep

    Black FUE scars are so small & scattered that they can not be easily seen 1 year with before and after donor 

  2. Black FUE Scars So Small & Scatttered Not Visible After Hair 

    Apr 9, 2013 – Uploaded by jgdiep

    Black FUE scars are so small & scattered that they can not be easily seen 1 year with before and after donor hair transplantrestoration surgery  

  3. FUE Hair Surgery Scars Back of The Head So Small Not Visible Hair 

    Apr 15, 2013 – Uploaded by jgdiep

    FUE No Visible Scars or minimal Scar donor result 1 year after hair  of The Head So Small Not Visible Hair Transplantwww.mhtaclinic.com.

Sources

FUE Hair Restoration through Robotics

Posted on

Dr. Sam Lam Utilizes ARTAS Hair Restoration System for FUE Hair Transplants in Dallas

http://www.hairtx.com

 

Plano, Texas   July 17, 2013   Health News

(PRLEAP.COM) Board-certified Dallas hair restoration surgeon Dr. Sam Lam, M.D., F.A.C.S., founder of the Lam Institute for Hair Restoration in Dallas, Texas, is now utilizing the revolutionary technology of the ARTASTM hair restoration system to perform follicular unit extraction (FUE) hair transplantation. This cutting-edge system is the first computer-assisted robotic technology that allows hair transplant surgeons to harvest hair follicles using minimally invasive techniques.

The ARTASTM system was developed by Restoration Robotics, Inc. and is the first technology of its kind. This innovative system is FDA cleared and allows for the extraction of hair follicles from the back of the head to be used in hair transplant procedures without the need for incisions. In addition to resulting in a procedure that causes less discomfort during the extraction of hair follicles, the ARTASTM system makes it more likely that healthy and strong follicular units will be selected, increasing the likelihood that hair follicles will successfully be transplanted.

Dr. Lam has long been at the forefront of the field of hair restoration, lecturing on his techniques and writing an international bestselling book on the topic, titled Hair Transplant 360. A key member of his hair transplant team, Emina Karamanovski, is equally skilled in the use of the ARTASTM system. Prior to joining the Lam Institute for Hair Restoration, Ms. Karamanovski was the national and international training director for Restoration Robotics and offers an unmatched level of experience and expertise with the ARTASTM system. The combination of Ms Karamanovski’s experience with ARTASTM and Dr. Lam’s exceptional hair restoration artistry provides a winning combination for patients of the Lam Institute.

“Hair restoration has always been a delicate combination of precision medical technique and creative artistry,” explains Dr. Sam Lam. “Many of my patients seek me out due to the reputation I have developed for creating natural-looking, dense and aesthetically appealing hair restorations. Now with the addition of the ARTASTM hair restoration system, as well as the expertise of Emina as part of our staff, we can achieve even better results. The ARTASTM system allows us to track and dissect the healthiest hair follicles, and since the procedure is so minimally invasive, the harvested follicles result in more successful transplantation.”

During the extraction portion of ARTASTM FUE hair transplants, the patient rests comfortably in an ergonomically designed chair and a skin tensioner is applied to the scalp. This stabilizes the patient’s skin, allowing computer-imaging technology to identify and target the follicular units to extract. The follicular units are extracted with no incision necessary, using minimally invasive techniques. Once harvested, the follicular units then undergo final preparation before being expertly grafted by Dr. Lam and his staff to complete the FUE hair restoration.

“A successful hair restoration is certainly about achieving a natural looking hairline,” says Dr. Lam. “But with the addition of the ARTASTM system for use during our follicular unit extraction procedures, we have now made it more comfortable for our patients to undergo the procedure while also making it more likely that the grafts that are harvested are strong and healthy, contributing to the likelihood that we will achieve denser and even more successful results.”

About Dr. Sam Lam:

Dallas hair restoration surgeon Dr. Sam Lam, founder and director of the Lam Institute of Hair Restoration, is one of only approximately one hundred Diplomates of the American Board of Hair Restoration Surgery. He has written over 150 scientific articles and book chapters, has authored five major medical textbooks, including a bestseller on hair transplantation titled Hair Transplant 360, and lectures about his hair restoration techniques around the globe. Dr. Lam is also the national course director for the Hair Transplant Course, an annual educational event in St. Louis, Missouri, has been distinguished as “Surgeon of the Month” by the International Society of Hair Restoration Surgery (ISHRS) and is a regular columnist for the Hair Transplant Forum International, the primary publication of the ISHRS. For additional information about Dr. Sam Lam and the Lam Institute for Hair Restoration, visit http://hairtx.com or call 972-3112-8188 or 1-888-866-3388.

CONTACT INFORMATION
Dr Samuel Lam
Hair Transplant Dallas
972-312-8188

Follicular Unit Extraction

FUE Hair Transplant:

Robotic Hair TransplantFollicular Unit Extraction (FUE), or FUE hair transplants, also known by other abbreviations: FOX, FIT, FUM, is a method of extracting hair from the donor area without an incision. Because there is no incision made, it has achieved popularity in the press. The advantages of FUE include the obviously stated one that there is no linear incision on the back of the head.  In addition, because there is no incision, the relative discomfort (feeling of tightness for the first week and some mild achiness) will be greatly diminished.  However, swelling in the forehead can be similar to a standard follicular-unit transplant (FUT) that uses linear harvesting of the donor area and that can last several days to a week following a procedure.  FUE is particularly helpful for those individuals who have active life styles and/or wear their hair short in which even a very good donor closure could still be visible to the naked eye.

ARTAS System (Robotic Follicular Unit Extraction [FUE]) for Hair Restoration

Dr. Lam combines his talents as a leader in the field of hair restoration with Emina Karamanovski, former national and international training director for Restoration Robotics, to offer the pre-eminent technology in no-incision, robotic hair transplant technology.

ARTAS: Precision Robotics, No-Incision Hair Restoration

The ARTAS System (from Restoration Robotics) is a computer-assisted, FDA-cleared, robotic device that offers the most precise method for follicular unit extraction (FUE) possible today. FUE refers to an incisionless method for harvesting hair from the back of the head in which individual follicular units are extracted one at a time. The advantages of the ARTAS system forhair restoration are as follows:

  • No linear incision or scarring along the back of the head
  • Precise, robot-controlled, consistent FUE harvesting
  • Hairstyle can be worn at any length without risk of exposing the donor scar
  • Nearly undetectable after a week
  • Quick return to sporting and other activities after a week.

 

Robotic technology has come of age to change the way that medicine is practiced today. Robotics has been implemented successfully in heart valve and bypass surgeries, prostate surgery, and kidney transplantation. Now computer-assisted robotic technology has arrived to change the landscape of hair restorationby offering the first consistent, reliable, and precise method of Follicular Unit Extraction (FUE). FUE has been gaining steady popularity over the last decade, especially in active men who desire to sport a shorter hairstyle. Since no linear incision is made on the back of the head, there is no risk of a linear scar.

Until the advent of robotic technology, the problem with FUE was the high degree of variability in harvesting quality that oftentimes led to poor, unpredictable hair transplant results. In particular, Dr. Lam believes that almost all previous methods of FUE have fallen short of his expectations for quality. Unlike older techniques like NEOGRAFT and hand harvesting for FUE, which are only powered tools, the image-guided robotic arm relies on a complex algorithm and multiple sensors that lead to unparalleled precision and speed in harvesting grafts at the ideal depth, angle and direction with optimal distance between grafts.

For ARTAS robotic-controlled FUE hair transplant procedures, the patient’s hair must be trimmed down to 1 mm in length in order for the imaging technology to identify and select the targeted follicular units for extraction. During harvesting, the patient rests comfortably in the ergonomically designed surgery chair, and a uniquely designed skin tensioner is applied to the patient’s scalp to stabilize the skin for accurate tracking and dissection of follicular units. After the harvesting is completed, Dr. Lam creates the recipient sites in an artistic manner to accommodate the harvested grafts. The grafts undergo final preparation and placement by Dr. Lam’s highly skilled, full-time and on-site hair-transplant staff. Recovery is quick and the donor area is healed and nearly undetectable within a week.

Despite the advanced state of robotic technology in the field of hair restoration, Dr. Lam believes that his artistic control over the design of your hair transplant pattern ultimately dictates the naturalness, visual density, and aesthetic appearance of your hair transplant. Always seeking to improve patient experience and outcome, Dr. Lam has been using healing and growth-promoting injections witnessing a revolution in his hair transplant results. Combining specialized platelet rich plasma (PRP) and Acell (morselized porcine basement membrane) and injecting them into the scalp, have increased the speed and percentage of hair growth. Since these injections improve quality of his hair transplantresults in a exceptional way, Dr. Lam uses them in almost every hair-transplant case whether it is performed via Robotic FUE or traditional strip harvesting.

With the combined experience of Emina Karamanovski, who has worked as the national and international training director for Restoration Robotics, Dr. Lam believes that he offers unparalleled experience and skill with the ARTAS system worldwide. Whether Dr. Lam performs standard strip harvesting or robotic FUE, he believes that he will provide you the most superior and natural results inhair restoration possible today.

FUE Hair Transplant Cost

Of course, FUE hair transplant cost is a concern for many when trying to determine if ARTAS FUE is the right procedure for them.  The good news is that FUE with ARTAS costs make it an affordable method for hair restoration.  Follicular unit extraction costs can be relatively similar to other forms ofhair restoration.  The exact cost of your FUE hair transplant will be discussed during an initial consultation with Dr. Lam.  During this consultation, your hair restoration needs and desires will be assessed by Dr. Lam and he will be able to provide you with an accurate overall FUE cost, based on the variety of factors that are unique to your case.

Every patient’s FUE hair transplant cost will be different, dependent primarily on how many hair grafts are required to achieve the level of coverage and density desired by the patient.  Although an exact follicular unit extraction cost cannot be provided as a generalization to cover all patients, we want to be as transparent as possible about FUE hair transplant pricing so you have some idea of what to expect. In general, patients can expect FUE pricing to be just over $7 per graft, although smaller procedures may incur a slightly higher per graft cost.  The FUE costs reflect a slight surcharge related to the use of the advanced ARTAS technology and the disposal costs that are incurred with each graft.